There are a number of preposition words that change the meaning of a phrase when used with a particular word. For example, you can use Irritated with different prepositions, and you will get a different meaning every time. You can see the examples below:
1. Irritated at
Irritated a t(thing)
Example: I was truly irritated at his unruly behaviour.
2. Irritated against
Irritated against (person)
Example:She was extremely irritated against her husband.